The Nevisense Platform 

The unique Nevisense platform – combinging Electrical Impedance Spectroscopy (EIS) in combination with AI – provides an in-depth analysis of the skin while being non-invasive. Today Nevisense point-of-care solution addresses three different areas; melanoma, keratinocyte and skin barrier assessment.
Nevisense can provide improved diagnostics, disease monitoring, and prediction in dermatology.

The Nevisense platform consists of  Nevisense and the smaller pen-size device Nevisense Go. Both perform electrical impedance measurements that reflects objective information on cellular structure, cellular orientation, size and other properties of the skin which are not available to any visual method for assessing skin barrier characteristics.

 

Nevisense Go

Nevisense Go is SciBase latest tool for measuring the electrical impedance of the skin. It´s a handheld, point-of-care device that is used for skin barrier assessment for studies

Nevisense Go is a handheld and fully portable device the size of a large pen. It combines the company’s core EIS measurement technology with a new AI-based analysis platform embedded in the device. Each measurement gathers 220 datapoints, from 1 kHz to 1MHz at 10 permutations and 4 depth settings, providing comprehensive analysis of the area being measured.

The result is a flexible tool that will allow easy collection of data and development of new applications.

The first Nevisense Go version is available for skin barrier assessment in research and clinical study applications and does not include a clinical indication (i.e. a non-medical device).

Nevisense Go provides a score after each measurement from an inbuilt AI classifier. It is also possible to download all measurement datapoints for further analysis and development, making Nevisense Go a powerful tool for skin barrier research.

Details:

Nevisense Go Handheld impedance meter with built in AI analysis
Size 190mm (h), 40mm (w), 25 mm (d), 1,3” (display)
Weight 120 grams
Product safety IEC 60601-1-2 Electromagnetic compatibility, IEC 62133-2
Connectivity Wi-Fi & Bluetooth capabilities
Battery Internal Lithium Polymer 3.7Wh.
Measurement frequencies 11 frequencies logarithmically distributed between 1kHz and 1MHz
Measurement levels Max measurement current = 10 µA
Max measurement voltage = 150 mV

 

Nevisense

Nevisense is a medical device with regulatory approval for detection of skin cancer, but can also be used for barrier research.

The Nevisense system consists of a control unit (1), a probe (2) and disposable electrodes (3). The control unit is used for user interaction through a touch screen and for signal processing of the impedance measurement signals, displaying the electrical impedance measurements on the screen.

Each measurement gathers 700 datapoints, from 1 kHz to 2,5 MHz at 10 permutations and 4 depth settings, providing comprehensive analysis of the area being measured.

It is possible to download all measurement datapoints for further analysis and development, making Nevisense a powerful tool for skin barrier research.

Nevisense  
Control unit screen The control unit has a 12” 800×600 color display with touch screen.
Measurement principle and frequencies Bioimpedance of the skin is measured micro invasively. Nevisense registers phase and magnitude in four different depths and ten permutations at 35 different frequencies from 1.0 kHz to 2.5 MHz.
Battery Battery status is indicated on the screen.
Control unit size 150 mm (h) x 400 mm (w) x 300 mm (d)
System weight Control unit 4 kg, probe unit 100g, battery 420g.
Product safety The CE-marked products fulfils the quality and safety regulations according to MDR for the clinical indication of skin cancer.
External interfaces The system is equipped with two USB ports.
Network Connectivity Nevisense supports connection to local area networks over Ethernet and WiFi.

 

 

Microinvasive electrode

SciBase´s proprietary disposable electrodes enable the electrical signals to reach the depths necessary to gather complete information about the properties of the skin.

The electrode has 5 gold plated bars with 45 microinvasive pins on each bar. The pins function is to penetrate into stratum corneum to warrant adequate electrical contact between the electrode and the underlying skin.

Each of the 5 bars of the electrode can send and receive electrical signals enabling complete coverage of the measurement area at 4 depths and 10 possible permutations over the frequency range of a measurement.

 

Nevisense Dashboard

The dashboard is a web-based visualization and analysis tool. Measurements can be exported from Nevisense or Nevisense Go and imported into the Dashboard.

In the dashboard, it is possible to

  • View and compare measurements,
  • Review all measurement data points (magnitude and phase shift over the measured frequencies)
  • Review calculated parameters, with features associated with bariier function, as well as any AI based analysis.
  • perform aggregate comparisons (scatter or boxplots) between selected parameters.
  • Export and import the data to/from Excel (where additional datatypes can be added and re-analyzed in the Dashboard